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After two months of development the "mini-brains" had become globular spheres up to four millimetres in diameter. Each one surrounded a ventricle-like inner cavity and mimicked the layered structure of a human brain growing within a developing foetus. Among the identifiable regions were a cerebral cortex, forebrain, choroid plexus - the body that produces cerebro-spinal fluid - and even a rudimentary retina. Tests showed that they contained active neurons. |
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